I have been experiencing this issue even before we upgraded to the 1.6.0.14 version.
The save button became available eventually but the the product would often not save the data on a product. Some tabs would work/save/load, the ones that don't work/save/load are: prices, associations and combinations.
As a e-commerce store, a resolution is important and necessary.
Has there been a fix?? or something I can tell my developers to do to resolve this issue??